The main directions of the research work at ACS are focused upon the following themes and topics:
- The U.S. and Armenia: Cooperation Frameworks and Strategies
- U.S. Regional Policies and Processes
- U.S. Regional Energy Policy: Regional Dimensions
- U.S.-Turkey Relations
- 2020 Karabakh War and the U.S. Policy in the Region
- Armenian Diaspora in the U.S.: state of the art and development vision